Drug General Information
Drug ID
D0B7OD
Former ID
DAP001452
Drug Name
Amfepramone
Synonyms
Adiposon; Amfepramon; Amfepramonum; Amphepramon; Amphepramone; Anfamon; Anfepramona; Anorex; Cegramine; DIETHYLPROPION; Danylen;Derfon; Diethylcathinone; Diethylpropione; Dobesin; Frekentine; Keramik; Keramin; Magrene; Modulor; Neobes; Nopropiophenone; Obesitex; Parabolin; Phepranon; Prefamone; Regenon; Reginon; Silutin; Tepanil; Tylinal; Amfepramone HCL; Amfepramone [INN]; Amfepramone hydrochloride; Amphepramonum hydrochloride; Diethylpropion HCL; Diethylpropione hydrochloride; Tenuate hydrochloride; UR 1423; Alpha-Benzoyltriethylamine; Alpha-Diethylaminopropiophenone; Amfepramone (INN); Amfepramonum [INN-Latin]; Anfepramona [INN-Spanish]; Diethylpropion (BAN); Fenyl-(1-diethylaminoethyl)keton; Fenyl-(1-diethylaminoethyl)keton [Czech]; (+-)-diethylpropion; 1-Phenyl-2-diethylamino-1-propanone; 2-(Diethylamino)-1-phenyl-1-propanone; 2-(Diethylamino)propiophenone; 2-(diethylamino)-1-phenylpropan-1-one; 2-Diethylaminopropiophenone
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Approved [536103]
Structure
Download
2D MOL

3D MOL

Formula
C13H19NO
Canonical SMILES
CCN(CC)C(C)C(=O)C1=CC=CC=C1
InChI
1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3
InChIKey
XXEPPPIWZFICOJ-UHFFFAOYSA-N
CAS Number
CAS 90-84-6
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
A08AA03
SuperDrug CAS ID
cas=000090846
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [536103]
Sodium-dependent noradrenaline transporter Target Info Inhibitor [536103]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter ActivityWP727:Monoamine Transport
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 536103Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418.
Ref 536103Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.