Drug General Information
Drug ID	D06CNP
Drug Name	Abiraterone acetate
Synonyms	CB-7630; JNJ-212082; Zytiga
Drug Type	Small molecular drug
Indication	Metastatic castration-resistant prostate cancer [ICD9: 140-229, 185; ICD10:C61]		Approved	[551871]
Therapeutic Class	Anticancer Agents
Structure		Download 2D MOL 3D MOL
Formula	C26H33NO2
PubChem Compound ID	9821849
Target and Pathway
Target(s)	17 alpha-hydroxylase-C17, 20-lyase	Target Info	Modulator
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Glucocorticoid biosynthesis
	Androgen biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
	Prolactin signaling pathway
PathWhiz Pathway	Androgen and Estrogen Metabolism
	Steroidogenesis
Reactome	Androgen biosynthesis
	Glucocorticoid biosynthesis
	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Steroid Biosynthesis
	Oxidation by Cytochrome P450
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
	Prostate Cancer
	Phase 1 - Functionalization of compounds
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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