TTD | Drug: D0N5TB

Drug General Information
Drug ID	D0N5TB
Former ID	DIB003599
Drug Name	ITRI-305
Synonyms	ITRI-305; RET tyrosine kinase inhibitors, Industrial Technology Research Institute
Indication	Thyroid cancer [ICD9: 140-229, 193; ICD10:C73]		Investigative	[543572]
Company	Industrial Technology Research Institute
Target and Pathway
Target(s)	Proto-oncogene tyrosine-protein kinase receptor ret	Target Info	Inhibitor	[543572]
KEGG Pathway	Endocytosis
	Pathways in cancer
	Thyroid cancer
	Central carbon metabolism in cancer
Pathway Interaction Database	Signaling events regulated by Ret tyrosine kinase
Pathway Interaction Database	Posttranslational regulation of adherens junction stability and dissassembly
WikiPathways	SIDS Susceptibility Pathways
WikiPathways	Dopaminergic Neurogenesis
References
Ref 543572	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2185).
Ref 543572	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2185).

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Drug Information