Drug Information

Drug General Information
Drug ID
D06PVN
Former ID
DIB015338
Drug Name
R-65
Synonyms
PGN-1473; R-65 (myometrial disorders), Asterand; R-65 (myometrial disorders), Pharmagene
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Investigative [543778]
Company
Pharmagene plc
Target and Pathway
Target(s) Prostaglandin E2receptor, EP2 subtype Target Info Modulator [543778]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
Renin secretion
Pathways in cancer
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543778(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 341).
Ref 543778(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 341).

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