Drug Information

Drug General Information
Drug ID
D0F3II
Former ID
DCL000090
Drug Name
COR100140
Drug Type
Small molecular drug
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Preclinical [547879]
Company
Cortical
Structure
Download
2D MOL

3D MOL
Formula
C38H40F7N9O3
Canonical SMILES
CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=<br />O)NN3)C4=CC=C(C=C4)F.CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=<br />N3
InChI
1S/C23H21F7N4O3.C15H19N5/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)37-20-19(13-2-4-17(24)5-3-13)34(6-7-36-20)11-18-31-21(35)33-32-18;1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H2,31,32,33,35);3-4,7-8,10-11,17H,5-6,9H2,1-2H3/t12-,19+,20-;/m1./s1
InChIKey
BALYAYJNMLHSJZ-IYOZAEJJSA-N
PubChem Compound ID
9853902
PubChem Substance ID
14815951, 45276209, 80593105, 134338787
Target and Pathway
Target(s) Macrophage migration inhibitory factor Target Info Inhibitor [550565]
KEGG Pathway Tyrosine metabolism
Phenylalanine metabolism
PathWhiz Pathway Tyrosine Metabolism
WikiPathways Spinal Cord Injury
Adipogenesis
References
Ref 547879Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020117)
Ref 550565Cortical Pty Ltd Presents MIF Antagonist Data at World Congress on Inflammation. Cortical Pty Ltd. 2005.

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