Drug Information
Drug General Information | |||||
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Drug ID |
D0X6AU
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Former ID |
DIB004420
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Drug Name |
FAS-031
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Synonyms |
FASi; FAS inhibitors (cancer); FAS-031; FAS-093; FAS-31; FAS-93; FAS inhibitors (cancer), FASgen/Johns Hopkins; Fatty acid synthase inhibitors (cancer), FASgen/Johns Hopkins; FAS inhibitors (cancer), FASgen/Johns Hopkins/Johnson & Johnson; Fatty acid synthase inhibitors (cancer), FASgen/Johns Hopkins/ Johnson & Johnson
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [543659] | ||
Company |
Johns Hopkins University
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Target and Pathway | |||||
Target(s) | Fatty acid synthase | Target Info | Inhibitor | [543659] | |
Pathway Interaction Database | p73 transcription factor network | ||||
Validated transcriptional targets of deltaNp63 isoforms | |||||
PathWhiz Pathway | Fatty Acid Biosynthesis | ||||
WikiPathways | Fatty Acid Biosynthesis | ||||
Nuclear Receptors Meta-Pathway | |||||
Liver X Receptor Pathway | |||||
Activation of Gene Expression by SREBP (SREBF) | |||||
SREBF and miR33 in cholesterol and lipid homeostasis | |||||
SREBP signalling | |||||
Metabolism of water-soluble vitamins and cofactors | |||||
Integration of energy metabolism | |||||
Fatty acid, triacylglycerol, and ketone body metabolism | |||||
AMPK Signaling | |||||
References |
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