Drug Information

Drug General Information
Drug ID
D0UF5H
Former ID
DIB008065
Drug Name
Dendrigen
Synonyms
Antiviral, Shanghai Genomics; Flt3 ligand (viral infection) Shanghai; Immunostimulant (viral infection), Shanghai
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Investigative [543494]
Company
Shanghai Genomics Inc
Structure
Download
2D MOL

3D MOL
Formula
C10H13N5O4
Canonical SMILES
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
InChI
1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChIKey
HBOMLICNUCNMMY-XLPZGREQSA-N
PubChem Compound ID
35370
PubChem Substance ID
9419, 595886, 596433, 596437, 596594, 596595, 597291, 597292, 597293, 597457, 597458, 597459, 597460, 597461, 597462, 597463, 597555, 597641, 597664, 597665, 600904, 601536, 602048, 622272, 624122, 643735, 644084, 855980, 7846195, 7847479, 7980906, 8149829, 8173993, 11335699, 11360938, 11364242, 11366804, 11369366, 11372752, 11373842, 11377528, 11461910, 11484570, 11488743, 11491322, 11492147, 11495162, 12013681, 12146009, 14799161
Target and Pathway
Target(s) FL cytokine receptor Target Info Binder [543494]
KEGG Pathway Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Central carbon metabolism in cancer
References
Ref 543494(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1807).
Ref 543494(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1807).

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