Drug General Information
Drug ID
D0A4XN
Former ID
DIB011540
Drug Name
PRS-639058
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Terminated [547996]
Company
Pharmos Corp
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [544486]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 547996Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021026)
Ref 544486Targeting CB2 receptors and the endocannabinoid system for the treatment of pain. Brain Res Rev. 2009 April; 60(1): 255-266.

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