Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03PCJ
|
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| Former ID |
DIB002379
|
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| Drug Name |
MPI-461359
|
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| Synonyms |
MPI-0461359; Antiviral (HIV infection), Myrexis; Antiviral (HIV infection), Myriad
|
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Terminated | [548769] | ||
| Company |
Myriad Genetics Inc
|
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| Target and Pathway | |||||
| Target(s) | HIV GAG protein | Target Info | Inhibitor | [531993] | |
| Reactome | Uncoating of the HIV Virion | ||||
| Budding and maturation of HIV virion | |||||
| Integration of provirus | |||||
| Early Phase of HIV Life Cycle | |||||
| Minus-strand DNA synthesis | |||||
| Plus-strand DNA synthesis | |||||
| 2-LTR circle formation | |||||
| Binding and entry of HIV virion | |||||
| Membrane binding and targetting of GAG proteins | |||||
| Assembly Of The HIV Virion | |||||
| Integration of viral DNA into host genomic DNA | |||||
| Autointegration results in viral DNA circles | |||||
| APOBEC3G mediated resistance to HIV-1 infection | |||||
| Vpr-mediated nuclear import of PICs | |||||
| WikiPathways | Host Interactions of HIV factors | ||||
| HIV Life Cycle | |||||
| References | |||||
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