Drug Information
Drug General Information | |||||
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Drug ID |
D03PKL
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Former ID |
DNCL003569
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Drug Name |
GSK933776
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Synonyms |
GSK-933776
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Indication | Geographic retinal atrophy; Macular degeneration [ICD9: 362.5; ICD10:H35.3] | Phase 2 | [523450] | ||
Company |
GlaxoSmithKline
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Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Modulator | [544153] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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