Drug General Information
Drug ID
D0L4VZ
Former ID
DIB009406
Drug Name
SPP-1148
Synonyms
SPP-1100; SPP-1193; Renin inhibitors (hypertension), Novartis; Renin inhibitors (hypertension), Speedel
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 1 [548440]
Company
Speedel Holding AG
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [544476]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 548440Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025565)
Ref 544476New Developments in the Pharmacological Treatment of Hypertension: Dead-End or a Glimmer at the Horizon?. Curr Hypertens Rep. 2015; 17(6): 42.

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