Drug Information

Drug General Information
Drug ID
D05CMZ
Former ID
DIB009499
Drug Name
ONO-2952
Synonyms
Translocator protein 18kDr (TSPO) antagonist (irritable bowel syndrome), Ono Pharmaceutical
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Phase 2 [524339]
Company
Ono Pharmaceutical Co Ltd
Structure
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2D MOL

3D MOL
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Antagonist [533291]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 524339ClinicalTrials.gov (NCT01887002) Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D). U.S. National Institutes of Health.
Ref 533291Anti-stress effects of ONO-2952, a novel translocator protein 18 kDa antagonist, in rats. Neuropharmacology. 2015 Jul 17;99:51-66.

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