Drug Information

Drug General Information
Drug ID
D0HX1T
Former ID
DIB009916
Drug Name
DA-697b
Synonyms
DZ-697b; Oral anticoagulants, Daiichi
Indication Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Phase 1 [530630]
Company
Daiichi Seiyaku Co Ltd
Target and Pathway
Target(s) Von Willebrand factor Target Info Inhibitor [530630]
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Complement and coagulation cascades
Platelet activation
PANTHER Pathway Blood coagulation
Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Integrin cell surface interactions
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
GP1b-IX-V activation signalling
MAP2K and MAPK activation
Platelet Adhesion to exposed collagen
WikiPathways Complement and Coagulation Cascades
Focal Adhesion
Blood Clotting Cascade
Platelet Adhesion to exposed collagen
Integrin alphaIIb beta3 signaling
GP1b-IX-V activation signalling
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 530630A new oral antiplatelet agent with potent antithrombotic properties: comparison of DZ-697b with clopidogrel a randomised phase I study. Thromb Haemost. 2010 Jan;103(1):205-12.
Ref 530630A new oral antiplatelet agent with potent antithrombotic properties: comparison of DZ-697b with clopidogrel a randomised phase I study. Thromb Haemost. 2010 Jan;103(1):205-12.

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