Drug Information

Drug General Information
Drug ID
D0I3RN
Former ID
DIB003822
Drug Name
PGL-2
Indication Endometriosis [ICD9: 617; ICD10:N80] Phase 2 [548563]
Company
ProSci
Target and Pathway
Target(s) Steryl-sulfatase Target Info Inhibitor [532697]
KEGG Pathway Steroid hormone biosynthesis
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Glycosphingolipid metabolism
WikiPathways Estrogen metabolism
Vitamin D Receptor Pathway
Sphingolipid metabolism
References
Ref 548563Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026648)
Ref 532697Synergistic effects of E2MATE and norethindrone acetate on steroid sulfatase inhibition: a randomized phase I proof-of-principle clinical study in women of reproductive age. Reprod Sci. 2014 Oct;21(10):1256-65.

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