TTD | Drug: D03JIH

Drug General Information
Drug ID	D03JIH
Former ID	DIB002560
Drug Name	SSR-125180
Indication	Obesity [ICD9: 278; ICD10:E66]		Discontinued in Phase 1	[547405]
Company	Sanofi-Synthelabo
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Agonist	[550839]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 547405	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015967)
Ref 550839	US patent application no. 8,748,419, Antagonists.

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Drug Information