Drug Information

Drug General Information
Drug ID
D01DTQ
Former ID
DIB017013
Drug Name
PXS-2076
Synonyms
PXS-2000; PXS-2030; Cannabinoid CB2 agonist (rheumatoid arthritis), Pharmaxis; TNFrelease inhibitor (rheumatoid arthritis), Pharmaxis
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Terminated [548079]
Company
Pharmaxis Ltd
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [543878]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 548079Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021746)
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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