Drug General Information
Drug ID	D09JXH
Former ID	DIB008576
Drug Name	LUM001
Synonyms	SHP625
Indication	Primary biliary cirrhosis [ICD9: 571.6; ICD10:K74.3]		Phase 2	[525031]
Company	Lumena pharmaceuticals
Structure		Download 2D MOL
Target and Pathway
Target(s)	Ileal bile acid transfer	Target Info	Inhibitor	[550354]
KEGG Pathway	Bile secretion
Reactome	Recycling of bile acids and salts
WikiPathways	Bile acid and bile salt metabolism
References
Ref 525031	ClinicalTrials.gov (NCT02321306) An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis. U.S. National Institutes of Health.
Ref 550354	Current research on the treatment of primary sclerosing cholangitis. Intractable Rare Dis Res. 2015 Feb; 4(1): 1-6.

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