Drug Information

Drug General Information
Drug ID
D0F8XK
Former ID
DPR000178
Drug Name
ISIS-GCCR
Drug Type
Antisense drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Preclinical [551052]
Company
ISIS Pharm
Target and Pathway
Target(s) mRNA of glucocorticoid receptor Target Info [551052]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL2 Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Signaling events mediated by HDAC Class II
FOXA2 and FOXA3 transcription factor networks
Glucocorticoid receptor regulatory network
Regulation of Androgen receptor activity
AP-1 transcription factor network
Reactome BMAL1:CLOCK,NPAS2 activates circadian gene expression
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
SIDS Susceptibility Pathways
Endoderm Differentiation
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Adipogenesis
Circadian Clock
Nuclear Receptors
References
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).

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