Drug General Information
Drug ID
D00FCV
Former ID
DIB013975
Drug Name
Inhaled liposomal ciprofloxacin
Indication Cystic fibrosis [ICD9: 277; ICD10:E84] Phase 2 [550263]
Company
Aradigm
Target and Pathway
Target(s) Topoisomerase IV subunit A Target Info Modulator [544493]
DNA gyraseA subunit Target Info Modulator [544493]
References
Ref 550263Inhaled Ciprofloxacin for the Management of Infections in Non-Cystic Fibrosis Bronchiectasis (BE) Patients
Ref 544493Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis. Antimicrob Agents Chemother. 2000 August; 44(8):2160-2165.

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