Drug General Information
Drug ID
D0J4PB
Former ID
DIB010834
Drug Name
GW 597599
Indication Mood disorder [ICD10:F30-F39] Phase 2 [547359]
Company
GlaxoSmithKline
Structure
Download
2D MOL
Target and Pathway
Target(s) Substance-P receptor Target Info Antagonist [530964]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 547359Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015473)
Ref 530964Application of LC-NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant). Magn Reson Chem. 2010 Jul;48(7):523-30.

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