Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01AVF
|
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| Former ID |
DIB002443
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| Drug Name |
SAR-106881
|
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| Synonyms |
FGF agonist (ischemia), sanofi-aventis
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| Indication | Peripheral arterial occlusive disease [ICD10:I73.9] | Investigative | [543495] | ||
| Company |
Sanofi
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C(=O)(c1ccc(c(c1)C(=O)O)N)c1c(c(c2ccccn12)NC(=O)c1cc(OC<br />C(=O)NCCNC(=O)COc2cccc(C(=O)Nc3c(c(C(=O)c4ccc(c(c4)C(=O<br />)O)N)n4ccccc34)C)c2)ccc1)C
|
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| Target and Pathway | |||||
| Target(s) | Basic fibroblast growth factor receptor 1 | Target Info | Agonist | [543495] | |
| KEGG Pathway | MAPK signaling pathway | ||||
| Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| FGF signaling pathway | |||||
| Pathway Interaction Database | Glypican 1 network | ||||
| Syndecan-4-mediated signaling events | |||||
| N-cadherin signaling events | |||||
| FGF signaling pathway | |||||
| References | |||||
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