Drug Information

Drug General Information
Drug ID
D0NH1E
Former ID
DIB000651
Drug Name
Org-231295
Synonyms
KDS-1243; KDS-4103; URB-597; FAAH inhibitor, Merck & Co; FAAH inhibitor, Schering-Plough/Kadmus/university of California
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Investigative [467677]
Company
University of California
Structure
Download
2D MOL

3D MOL
Formula
C20H22N2O3
InChI
InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChIKey
ROFVXGGUISEHAM-UHFFFAOYSA-N
PubChem Compound ID
1383884
PubChem Substance ID
1712159, 4117632, 6954439, 8844535, 14875581, 26758692, 29217673, 39816644, 47204541, 50076611, 50622803, 53790751, 53800779, 56365487, 57298451, 57409005, 89062649, 103455066, 103867351, 105221266, 110370747, 118265378, 124360783, 124582512, 125160794, 125164696, 125334103, 131318389, 134345885, 135246806, 135367488, 135683180, 136340244, 136349528, 136367659, 136373638, 137125269, 137189432, 139529511, 152258271, 152344299, 160647108, 162011484, 162035022, 162194395, 163125113, 163688151, 164194104, 164195801, 165437862
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [543418]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signaling
PANTHER Pathway Anandamide degradation
References
Ref 467677(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4339).
Ref 543418(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1400).

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