Drug Information
Drug General Information | |||||
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Drug ID |
D0VY5O
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Former ID |
DIB000635
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Drug Name |
A-620223
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Synonyms |
A-866111; A-966492; ABT-472; ABT-999; PARP inhibitor, Abbott; PARP inhibitors, Abbott; Poly (ADP)ribose polymer inhibitor, Abbott; Poly (ADP)ribose inhibitors (cancer), Abbott
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Drug Type |
Small molecular drug
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [543709] | ||
Company |
Abbott Laboratories
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Structure |
Download2D MOL |
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Formula |
C16H22N4O
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Canonical SMILES |
c12c([nH]c(n2)C2CCN(CC2)CCC)cccc1C(=O)N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Poly [ADP-ribose] polymerase-1 | Target Info | Inhibitor | [543709] | |
KEGG Pathway | Base excision repair | ||||
NF-kappa B signaling pathway | |||||
PANTHER Pathway | FAS signaling pathway | ||||
Pathway Interaction Database | Integrin-linked kinase signaling | ||||
Caspase Cascade in Apoptosis | |||||
Notch-mediated HES/HEY network | |||||
Reactome | Dual Incision in GG-NER | ||||
References |
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