Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J6AU
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| Former ID |
DCL000568
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| Drug Name |
Odanacatib
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| Synonyms |
Odanacatib; MK 0822; MK0822; MK-0822A; Odanacatib (USAN)
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| Drug Type |
Small molecular drug
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| Indication | Ostereoporosis [ICD9: 733; ICD10:M80-M81] | Phase 1 | [548318] | ||
| Company |
Merck
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| Structure |
|
Download2D MOL |
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| Formula |
C25H27F4N3O3S
|
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| Canonical SMILES |
CC(C)(CC(C(=O)NC1(CC1)C#N)NC(C2=CC=C(C=C2)C3=CC=C(C=C3)<br />S(=O)(=O)C)C(F)(F)F)F
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| InChI |
1S/C25H27F4N3O3S/c1-23(2,26)14-20(22(33)32-24(15-30)12-13-24)31-21(25(27,28)29)18-6-4-16(5-7-18)17-8-10-19(11-9-17)36(3,34)35/h4-11,20-21,31H,12-14H2,1-3H3,(H,32,33)/t20-,21-/m0/s1
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| InChIKey |
FWIVDMJALNEADT-SFTDATJTSA-N
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| CAS Number |
CAS 603139-19-1Topotecan
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| PubChem Compound ID | |||||
| PubChem Substance ID |
15144761, 22552176, 40136829, 77239026, 96025638, 99431578, 103609745, 104107486, 124759704, 126644892, 126671643, 135252258, 136024159, 136345874, 136367854, 137251867, 139992214, 144116308, 152040138, 152258027, 152258070, 152344369, 160646909, 162038064, 162205218, 164023439, 164210447, 170502111, 174006242, 178103092, 184823532, 198938642, 223386751, 223675719, 223704695, 223842901, 227700968, 242591563, 244396141, 251970964, 252160437
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | Inhibitor | [536569], [549718] | |
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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