Drug General Information
Drug ID
D0ZD3C
Former ID
DIB016028
Drug Name
Gemigliptin
Drug Type
Small molecular drug
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Phase 3 [524534]
Company
LG Life Sciences Ltd
Structure
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2D MOL

3D MOL

Formula
C18H19F8N5O2
Canonical SMILES
C1CN(Cc2c1c(nc(n2)C(F)(F)F)C(F)(F)F)C(=O)C[C@@H](CN1C(=<br />O)CCC(C1)(F)F)N
PubChem Compound ID
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [533009]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 524534ClinicalTrials.gov (NCT01990469) Efficacy and Safety of Gemigliptin 50mg qd Added in Patients With Type 2 Diabetes Inadequately Controlled on Glimepiride and Metformin. U.S. National Institutes of Health.
Ref 533009Evaluation of the pharmacokinetics of the DPP-4 inhibitor gemigliptin when coadministered with rosuvastatin or irbesartan to healthy subjects. Curr Med Res Opin. 2015 Feb;31(2):229-41.

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