Drug Information
Drug General Information | |||||
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Drug ID |
D0P1YE
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Former ID |
DCL000585
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Drug Name |
Orvepitant
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Drug Type |
Small molecular drug
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Indication | Depression; Anxiety [ICD9: 300, 311; ICD10:F30-F39, F40-F42] | Phase 2 | [547887] | ||
Company |
GSK
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Structure |
Download2D MOL |
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Formula |
C31H35F7N4O2
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Canonical SMILES |
CC1=C(C=CC(=C1)F)C2CC(CCN2C(=O)N(C)C(C)C3=CC(=CC(=C3)C(<br />F)(F)F)C(F)(F)F)N4CCN5C(C4)CCC5=O
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InChI |
1S/C31H35F7N4O2/c1-18-12-23(32)4-6-26(18)27-16-24(40-10-11-41-25(17-40)5-7-28(41)43)8-9-42(27)29(44)39(3)19(2)20-13-21(30(33,34)35)15-22(14-20)31(36,37)38/h4,6,12-15,19,24-25,27H,5,7-11,16-17H2,1-3H3/t19-,24+,25+,27-/m1/s1
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InChIKey |
XWNBGDJPEXZSQM-VZOBGQTKSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Antagonist | [550963] | |
PANTHER Pathway | CCKR signaling map ST | ||||
Reactome | G alpha (q) signalling events | ||||
References |
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