Drug Information

Drug General Information
Drug ID
D09XGB
Former ID
DNC002370
Drug Name
VER 50589
Drug Type
Small molecular drug
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Phase 2 [532267]
Therapeutic Class
Anticancer Agents
Structure
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2D MOL

3D MOL
Formula
C19H17ClN2O5
Canonical SMILES
CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)Cl)ON1)C3=CC=C(C=C3)OC
InChI
1S/C19H17ClN2O5/c1-3-21-19(25)17-16(10-4-6-11(26-2)7-5-10)18(27-22-17)12-8-13(20)15(24)9-14(12)23/h4-9,22,24H,3H2,1-2H3,(H,21,25)/b18-12-
InChIKey
DGNFSLDDDQFHNU-PDGQHHTCSA-N
PubChem Compound ID
16058668
PubChem Substance ID
24902651, 26718080, 40649505, 49688973, 87557387, 99443435, 103556560, 137220202, 140671845, 160968050, 163422681, 163852188, 163893856, 172893284, 190861989, 210275466, 210281114, 252465470, 252470155
Target and Pathway
Target(s) Heat shock protein HSP90 Target Info Inhibitor [536886]
References
Ref 532267The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. Mol Cancer Ther. 2013 Jun;12(6):890-900.
Ref 536886Recent advances in Hsp90 inhibitors as antitumor agents. Anticancer Agents Med Chem. 2008 Oct;8(7):761-82.

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