Drug Information

Drug General Information
Drug ID
D0V8HA
Former ID
DAP000027
Drug Name
Mecamylamine
Synonyms
Mecamilamina; Mecamine; Mecamylaminum; Mekamine; Mevasine; Revertina; Versamine; Inversine hydrochloride; Mecamilamina [DCIT]; Mecamilamina [Italian]; Mevasin hydrochloride; Inversine (TN); Mecamylamine [INN:BAN]; Mecamylaminum [INN-Latin]; N-Methyl-2-isocamphanamine; N,2,3,3-Tetramethyl-2-norbornamine; N,2,3,3-Tetramethyl-2-norcamphanamine; N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine; (+)-Mecamylamine; (-)-Mecamylamine; 2-Methylamino-2,3,3-trimethylnorbornane; 2-Methylaminoisocamphane; 3-Methylaminoisocamphane; 3-Methylaminoisokamfan; 3-Methylaminoisokamfan [Czech]; 3-beta-Methylamino-2,2,3-trimethylbicyclo(2.2.1)heptane
Drug Type
Small molecular drug
Indication Moderately severe to severe essential hypertension [ICD10:I10] Approved [551871]
Therapeutic Class
Antihypertensive Agents
Company
Mecamylamine
Structure
Download
2D MOL

3D MOL
Formula
C11H21N
InChI
InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3
InChIKey
IMYZQPCYWPFTAG-UHFFFAOYSA-N
CAS Number
CAS 60-40-2
PubChem Compound ID
4032
PubChem Substance ID
9714, 3249412, 4782131, 8152523, 11342007, 11362190, 11363198, 11365760, 11368322, 11371612, 11374952, 11376484, 11467139, 11468259, 11486847, 11487592, 11490552, 11493071, 11494118, 14748127, 26755706, 29223143, 46508607, 47365386, 47365387, 47365388, 47440440, 47440441, 47885580, 48110632, 48416199, 49698966, 49998070, 50111169, 50813825, 53788079, 57322103, 90341710, 103164508, 103826601, 103957127, 104171190, 104305231, 108209719, 118270204, 124589602, 124750040, 124880783, 125823670, 128191225
SuperDrug ATC ID
C02BB01
SuperDrug CAS ID
cas=000060402
Target and Pathway
Target(s) Nicotinic acetylcholine receptor Target Info Antagonist [535489]
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535489Mecamylamine (Inversine): an old antihypertensive with new research directions. J Hum Hypertens. 2002 Jul;16(7):453-7.

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