Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0G6ZG
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| Former ID |
DCL000691
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| Drug Name |
Amediplase
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| Synonyms |
Amediplase [INN]; Trans,trans-3,4:12,13-Tetrahydroxy-3,4,12,13-tetrahydro-dibenz(a,h)anthracene; (3S,4S,12S,13S)-3,4,12,13-tetrahydronaphtho[1,2-b]phenanthrene-3,4,12,13-tetrol
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| Drug Type |
Small molecular drug
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| Company |
Menarini
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| Structure |
|
Download2D MOL |
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| Formula |
C22H18O4
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C(C(C3=C2C=C4C=CC5=C(C4=C3)C=CC(C5O)O)O)O
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| InChI |
1S/C22H18O4/c23-19-8-7-13-15(20(19)24)6-5-11-9-17-12-3-1-2-4-14(12)21(25)22(26)18(17)10-16(11)13/h1-10,19-26H/t19-,20-,21-,22-/m0/s1
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| InChIKey |
YQINXCSNGCDFCQ-CMOCDZPBSA-N
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| CAS Number |
CAS 151912-11-7
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
B01AC07
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| SuperDrug CAS ID |
cas=000058322
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| Target and Pathway | |||||
| Target(s) | Urokinase-type plasminogen activator | Target Info | Activator | [536186] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Pathway Interaction Database | Beta1 integrin cell surface interactions | ||||
| E2F transcription factor network | |||||
| Beta3 integrin cell surface interactions | |||||
| Osteopontin-mediated events | |||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| amb2 Integrin signaling | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| Beta2 integrin cell surface interactions | |||||
| Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||||
| Beta5 beta6 beta7 and beta8 integrin cell surface interactions | |||||
| FGF signaling pathway | |||||
| Reactome | Dissolution of Fibrin Clot | ||||
| References | |||||
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