Drug Information

Drug General Information
Drug ID
D0V0SL
Former ID
DNCL002505
Drug Name
Abexinostat
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 2 [543092], [548180]
Company
Pharmacyclics
Structure
Download
2D MOL

3D MOL
Formula
C21H23N3O5
InChI
InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
InChIKey
MAUCONCHVWBMHK-UHFFFAOYSA-N
PubChem Compound ID
11749858
PubChem Substance ID
16857486, 23832872, 42791900, 56269573, 80326339, 117695997, 124756990, 125163795, 131480753, 134223063, 134964420, 135267137, 135626780, 136340216, 136367289, 136367841, 136920360, 137216456, 139896178, 144116341, 152258290, 152344189, 160647129, 160681721, 162011829, 162037426, 162202783, 163907942, 164041979, 164193977, 172914354, 174006344, 174530736, 175426351, 177748391, 186014504, 198941643, 201507997, 223381303, 223705150, 224769568, 226766445, 248596262, 252166578, 252215998, 252220173, 252671930
Target and Pathway
Target(s) Histone deacetylase Target Info Modulator [533112]
References
Ref 543092(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8366).
Ref 548180Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022814)
Ref 533112Phase 1 study of the oral histone deacetylase inhibitor abexinostat in patients with Hodgkin lymphoma, non-Hodgkin lymphoma, or chronic lymphocytic leukaemia. Invest New Drugs. 2015 Apr;33(2):423-31.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.