Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0WH9U
|
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| Former ID |
DIB008486
|
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| Drug Name |
FK-070
|
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| Drug Type |
Small molecular drug
|
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| Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Phase 2 | [534202] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H27Cl2N3O4S
|
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| Canonical SMILES |
C1C(CN(C1C=CCCCC(=O)O)CC2=CN=CC=C2)NS(=O)(=O)C3=CC=C(C=<br />C3)Cl.Cl
|
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| InChI |
1S/C22H26ClN3O4S.ClH/c23-18-8-10-21(11-9-18)31(29,30)25-19-13-20(6-2-1-3-7-22(27)28)26(16-19)15-17-5-4-12-24-14-17;/h2,4-6,8-12,14,19-20,25H,1,3,7,13,15-16H2,(H,27,28);1H/b6-2-;/t19-,20-;/m1./s1
|
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| InChIKey |
JGCFJVFIRFTRKJ-YOLZMAEBSA-N
|
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| CAS Number |
CAS 130047-27-7
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Thromboxane A2 receptor | Target Info | Modulator | [534202] | |
| Thromboxane-A synthase | Target Info | Modulator | [534202] | ||
| BioCyc Pathway | C20 prostanoid biosynthesis | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Small Ligand GPCRs | |||||
| Signal amplification | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP98:Prostaglandin Synthesis and Regulation | |||||
| Arachidonic acid metabolism | |||||
| Phase 1 - Functionalization of compounds | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
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