Drug Information

Drug General Information
Drug ID
D04GLJ
Former ID
DIB006529
Drug Name
OCFENTANIL
Synonyms
Ocfentanil < Rec INN; A-3217 (hydrochloride); N-(2-Fluorophenyl)-2-methoxy-N-[1-(2-phenylethyl)-4-piperidinyl]acetamide; 1-(2-Phenylethyl)-4-[N-(2-fluorophenyl)methoxyacetamido]piperidine; 2'-Fluoro-2-methoxy-N-(1-phenethyl-4-piperidinyl)acetanilide
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Phase 2 [531161]
Structure
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2D MOL

3D MOL
Formula
C22H28ClFN2O2
Canonical SMILES
COCC(=O)N(C1CCN(CCc2ccccc2)CC1)c3ccccc3F
InChIKey
NYISTOZKVCMVEL-UHFFFAOYSA-N
CAS Number
CAS 101343-69-5
PubChem Compound ID
9931207
Target and Pathway
Target(s) Opioid receptor Target Info Modulator [530205], [551871]
References
Ref 531161A phase II clinical study of once-a-day fentanyl citrate patch in patients with cancer pain--switching from once-every-three-days fentanyl patch to once-a-day fentanyl citrate patch. Gan To Kagaku Ryoho. 2010 Sep;37(9):1747-52.
Ref 530205Comparison of ocfentanil and fentanyl as supplements to general anesthesia. Anesth Analg. 1991 Nov;73(5):622-6.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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