Drug Information
Drug General Information | |||||
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Drug ID |
D0QG2D
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Former ID |
DCL000042
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Drug Name |
Amelubant
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Synonyms |
Amelubant [INN]; BIIL 283 BS; BIIL 284; Ethyl ((4-((3-((4-(1-(4-hydroxyphenyl)-1-methylethyl)phenoxy)methyl)benzyl)oxy)phenyl)(imino)methyl)carbamate; Carbamic acid, ((4-((3-((4-(1-(4-hydroxyphenyl)-1-methylethyl)phenoxy)methyl)phenyl)methoxy)phenyl)iminomethyl)-, ethyl ester
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Drug Type |
Small molecular drug
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Company |
Boehringer Ingelheim
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Structure |
Download2D MOL |
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Formula |
C33H34N2O5
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InChI |
InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37)
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InChIKey |
SBVYURPQULDJTI-UHFFFAOYSA-N
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CAS Number |
CAS 346735-24-8
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Leukotriene B4 receptor 1 | Target Info | Antagonist | [536071], [536162] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
NetPath Pathway | IL4 Signaling Pathway | ||||
References | |||||
Ref 524934 | ClinicalTrials.gov (NCT02251210) Efficacy and Safety of BIIL 284 BS in Adult Patients With Active Rheumatoid Arthritis. U.S. National Institutes of Health. | ||||
Ref 543153 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8463). |
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