TTD | Drug: D02XYB

Drug General Information
Drug ID	D02XYB
Former ID	DIB002353
Drug Name	SARIPIDEM
Synonyms	SL-85.0274; Saripidem < Rec INN >; N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-ylmethyl]-N-methylbutanamide
Drug Type	Small molecular drug
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Phase 2	[525986]
Structure		Download 2D MOL 3D MOL
Formula	C19H20ClN3O
Canonical SMILES	CCCC(=O)N(C)Cc1c(nc2ccccn12)c3ccc(Cl)cc3
InChI	1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(20)11-9-14)21-17-7-4-5-12-23(16)17/h4-5,7-12H,3,6,13H2,1-2H3
InChIKey	LIFDPEORUVTOCP-UHFFFAOYSA-N
CAS Number	CAS 103844-86-6
PubChem Compound ID	3058746
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[525986]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 525986	Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue. Behav Pharmacol. 1995 Mar;6(2):116-126.
Ref 525986	Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue. Behav Pharmacol. 1995 Mar;6(2):116-126.

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Drug Information