Drug Information
Drug General Information | |||||
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Drug ID |
D0E1VV
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Former ID |
DIB005543
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Drug Name |
ELOMOTECAN HYDROCHLORIDE
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Synonyms |
BN-80927; R-1559; Elomotecan hydrochloride < Prop INNM >; (+)-9-Chloro-5(R)-ethyl-5-hydroxy-10-methyl-12-(4-methylpiperidin-1-ylmethyl)-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione hydrochloride
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Drug Type |
Small molecular drug
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Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Phase 1 | [523624] | ||
Structure |
Download2D MOL |
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Formula |
C29H33Cl2N3O4
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Canonical SMILES |
CCC1(CC(=O)OCC2=C1C=C3C4=NC5=CC(=C(C=C5C(=C4CN3C2=O)CN6<br />CCC(CC6)C)C)Cl)O.Cl
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InChI |
1S/C29H32ClN3O4.ClH/c1-4-29(36)12-26(34)37-15-21-22(29)10-25-27-20(14-33(25)28(21)35)19(13-32-7-5-16(2)6-8-32)18-9-17(3)23(30)11-24(18)31-27;/h9-11,16,36H,4-8,12-15H2,1-3H3;1H/t29-;/m1./s1
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InChIKey |
OLYFGLXPXPABOP-XXIQNXCHSA-N
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CAS Number |
CAS 220997-99-9
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Modulator | ||
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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