Drug Information
Drug General Information | |||||
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Drug ID |
D05GUK
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Former ID |
DIB009869
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Drug Name |
INTOPLICINE
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Synonyms |
RP-60475; Intoplicine < Rec INN >; 11-[3-(Dimethylamino)propylamino]-8-methyl-7H-benzo[e]pyrido[4,3-b]indol-3-ol
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Drug Type |
Small molecular drug
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Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Phase 1 | [521454] | ||
Structure |
Download2D MOL |
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Formula |
C21H24N4O
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Canonical SMILES |
CN(C)CCCNc1ncc(C)c2[nH]c3ccc4cc(O)ccc4c3c12
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InChI |
1S/C21H24N4O/c1-13-12-23-21(22-9-4-10-25(2)3)19-18-16-7-6-15(26)11-14(16)5-8-17(18)24-20(13)19/h5-8,11-12,24,26H,4,9-10H2,1-3H3,(H,22,23)
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InChIKey |
QROONAIPJKQFMC-UHFFFAOYSA-N
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CAS Number |
CAS 125974-72-3
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Modulator | ||
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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