Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I4OX
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| Former ID |
DIB006144
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| Drug Name |
SURADISTA
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| Synonyms |
PNU-145156E; FCE-26644 (formerly); PNU-151484 (Na salt); 7,7'-[Carbonylbis[imino(1-methyl-1H-pyrrole-4,2-diyl)carbonylimino(1-methyl-1H-pyrrole-4,2-diyl)carbonylimino]]bis-1,3-naphthalenedisulfonic acid tetrapotassium salt; 7,7-Ureylene-bis(1-methyl-4,2-pyrrolecarboxamido)bis(1-methyl-4,2-pyrrolecarboxamido)bis(1,3-naphthalenedisulfonic acid) tetrapotassium salt
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| Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Discontinued in Phase 1 | [545728] | ||
| Structure |
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Download2D MOL |
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| Canonical SMILES |
Cn1cc(NC(=O)Nc2cc(C(=O)Nc3cc(C(=O)Nc4ccc5cc(cc(c5c4)S(=<br />O)(=O)O)S(=O)(=O)O)n(C)c3)n(C)c2)cc1C(=O)Nc6cc(C(=O)Nc7<br />ccc8cc(cc(c8c7)S(=O)(=O)O)S(=O)(=O)O)n(C)c6
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| InChI |
1S/C45H40N10O17S4/c1-52-19-27(13-35(52)41(56)46-25-7-5-23-9-31(73(61,62)63)17-39(33(23)11-25)75(67,68)69)48-43(58)37-15-29(21-54(37)3)50-45(60)51-30-16-38(55(4)22-30)44(59)49-28-14-36(53(2)20-28)42(57)47-26-8-6-24-10-32(74(64,65)66)18-40(34(24)12-26)76(70,71)72/h5-22H,1-4H3,(H,46,56)(H,47,57)(H,48,58)(H,49,59)(H2,50,51,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)
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| InChIKey |
WQHXQLSSMJYNOJ-UHFFFAOYSA-N
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| CAS Number |
CAS 136714-83-5
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| Target and Pathway | |||||
| Target(s) | C-X-C chemokine receptor 4 | Target Info | Modulator | [526483] | |
| References | |||||
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