Drug Information

Drug General Information
Drug ID
D0R2HZ
Former ID
DIB004557
Drug Name
ETHOXY-IDAZOXAN
Synonyms
RX-811059; 2-(2-Ethoxy-1,4-benzodioxan-2-yl)-1-imidazoline
Drug Type
Small molecular drug
Indication Poison intoxication [ICD10:T36-T50] Investigative [531785]
Structure
Download
2D MOL

3D MOL
Formula
C13H16N2O3
Canonical SMILES
CCOC1(COC2=CC=CC=C2O1)C3=NCCN3
InChI
1S/C13H16N2O3/c1-2-17-13(12-14-7-8-15-12)9-16-10-5-3-4-6-11(10)18-13/h3-6H,2,7-9H2,1H3,(H,14,15)
InChIKey
PXTLRBYNGGDZBN-UHFFFAOYSA-N
CAS Number
CAS 96576-24-8
PubChem Compound ID
125992
PubChem Substance ID
10241475, 14971043, 29305671, 47285927, 48254035, 50768981, 57341591, 85216877, 103103566, 104362651, 117604407, 128983653, 131342377, 135081500, 163112021, 179293701, 236056319, 242108214
Target and Pathway
Target(s) Alpha-2C adrenergic receptor Target Info Modulator [531785]
KEGG Pathway cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Alpha adrenergic receptor signaling pathway
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome Adrenoceptors
Adrenaline signalling through Alpha-2 adrenergic receptor
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (i) signalling events
G alpha (z) signalling events
Surfactant metabolism
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Platelet Aggregation (Plug Formation)
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 531785Discriminative stimulus properties of ethoxy idazoxan. J Psychopharmacol. 1995 Jan;9(3):228-33.
Ref 531785Discriminative stimulus properties of ethoxy idazoxan. J Psychopharmacol. 1995 Jan;9(3):228-33.

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