Drug Information
Drug General Information | |||||
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Drug ID |
D0YB2Y
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Former ID |
DNCL002051
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Drug Name |
AMG 853
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Drug Type |
Small molecular drug
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Indication | Asthma [ICD10:J45] | Phase 2 | [522862] | ||
Company |
Amgen Thousand
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Structure |
Download2D MOL |
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Formula |
C28H27Cl2FN2O6S
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Canonical SMILES |
CC(C)(C)NC(=O)C1=CC(=C(C=C1)OC2=C(C=C(C(=C2)F)CC(=O)O)C<br />l)NS(=O)(=O)C3=C(C=C(C=C3)C4CC4)Cl
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InChI |
1S/C28H27Cl2FN2O6S/c1-28(2,3)32-27(36)17-6-8-23(39-24-14-21(31)18(11-19(24)29)13-26(34)35)22(12-17)33-40(37,38)25-9-7-16(10-20(25)30)15-4-5-15/h6-12,14-15,33H,4-5,13H2,1-3H3,(H,32,36)(H,34,35)
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InChIKey |
PFWVGKROPKKEDW-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Putative G-protein coupled receptor 44 | Target Info | Modulator | ||
Prostaglandin D2 receptor | Target Info | Modulator | |||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
PathWhiz Pathway | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | ||||
References |
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