Drug General Information
Drug ID	D0R3OR
Former ID	DIB016655
Drug Name	SR-27950
Synonyms	SR-27899
Indication	Eating disorder [ICD9: 278, 307.5, 401, 428.0; ICD10:E66, F50, I10-I16, I50]		Terminated	[544831]
Company	Sanofi
Structure		Download 2D MOL 3D MOL
Canonical SMILES	n1(c(C(=O)N[C@H]2N=C(c3c(NC2=O)cccc3)c2ccccc2)cc2c1cccc<br />2)CC(=O)O
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Modulator	[543960]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544831	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001260)
Ref 543960	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 76).

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