Drug Information

Drug General Information
Drug ID
D0D3KY
Former ID
DIB003706
Drug Name
SC-106
Drug Type
Small molecular drug
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Discontinued in Phase 2 [546279]
Company
Scotia Holdings plc
Structure
Download
2D MOL

3D MOL
Formula
C15H17N5O4
Canonical SMILES
C#CC(CC(=O)O)NC(=O)CNC(=O)C1=CC(=CC=C1)N=C(N)N
InChI
1S/C15H17N5O4/c1-2-10(7-13(22)23)19-12(21)8-18-14(24)9-4-3-5-11(6-9)20-15(16)17/h1,3-6,10H,7-8H2,(H,18,24)(H,19,21)(H,22,23)(H4,16,17,20)/t10-/m0/s1
InChIKey
IABCGGIFHPDBCJ-JTQLQIEISA-N
PubChem Compound ID
492984
PubChem Substance ID
218732, 15470693, 38680925, 79661834, 109759802, 128137880, 143362204, 232462977
Target and Pathway
Target(s) Phospholipase A2 Target Info Inhibitor [550919]
BioCyc Pathway Phospholipases
KEGG Pathway Glycerophospholipid metabolism
Ether lipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
alpha-Linolenic acid metabolism
Metabolic pathways
Ras signaling pathway
Vascular smooth muscle contraction
Pancreatic secretion
Fat digestion and absorption
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
Reactome Acyl chain remodelling of PC
Acyl chain remodelling of PE
Acyl chain remodelling of PI
WikiPathways Glycerophospholipid biosynthesis
References
Ref 546279Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007225)
Ref 550919US patent application no. 6,673,908, Tumor necrosis factor receptor 2.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.