Drug Information
Drug General Information | |||||
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Drug ID |
D0D4CX
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Former ID |
DIB012229
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Drug Name |
Pegamotecan
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Synonyms |
Prothecan; EZ-246; PEG-camptothecin; PEG-camptothecin, Enzon; Polyethylene glycol-camptothecin, Enzon
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Drug Type |
Small molecular drug
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Indication | Esophageal cancer [ICD9: 150; ICD10:C15] | Phase 2 | [521591] | ||
Company |
Enzon Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Formula |
C53H50N6O13
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Canonical SMILES |
[C@@]1(C(=O)OCc2c1cc1n(c2=O)Cc2c1nc1c(c2)cccc1)(OC(=O)[<br />C@@H](NC(=O)COCCOCC(=O)N[C@H](C(=O)O[C@@]1(C(=O)OCc2c1c<br />c1n(c2=O)Cc2c1nc1c(c2)cccc1)CC)C)C)CC
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [529412] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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