Drug Information

Drug General Information
Drug ID
D0E4FM
Former ID
DNC003212
Drug Name
Y-700
Drug Type
Small molecular drug
Indication Gout [ICD9: 274.00274.1274.8274.9; ICD10:M10] Discontinued in Phase 2 [546844]
Structure
Download
2D MOL

3D MOL
Formula
C16H17N3O3
Canonical SMILES
CC(C)(C)COC1=C(C=C(C=C1)N2C=C(C=N2)C(=O)O)C#N
InChI
1S/C16H17N3O3/c1-16(2,3)10-22-14-5-4-13(6-11(14)7-17)19-9-12(8-18-19)15(20)21/h4-6,8-9H,10H2,1-3H3,(H,20,21)
InChIKey
AETHRPHBGJAIBT-UHFFFAOYSA-N
PubChem Compound ID
449035
PubChem Substance ID
585523, 7891204, 14922860, 36890716, 46506546, 51173966, 103428343, 103995159, 104640327, 127395924, 135262839, 135697671, 137183688, 137275979, 160966921, 198979848, 223704873, 225063631, 226762823, 252159928
Target and Pathway
Target(s) Xanthine dehydrogenase/oxidase Target Info Inhibitor [551374]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides degradation
Adenosine nucleotides degradation
Retinoate biosynthesis II
KEGG Pathway Purine metabolism
Caffeine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Peroxisome
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Purine metabolism
PathWhiz Pathway Caffeine Metabolism
Purine Metabolism
Reactome Purine catabolism
WikiPathways Oxidative Stress
Effects of Nitric Oxide
Metabolism of nucleotides
Selenium Micronutrient Network
References
Ref 546844Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010582)
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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