Drug Information

Drug General Information
Drug ID
D0PW4C
Former ID
DNC001021
Drug Name
Niravoline
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Phase 2 [545439]
Structure
Download
2D MOL

3D MOL
Formula
C22H25N3O3
Canonical SMILES
CN(C1C(CC2=CC=CC=C12)N3CCCC3)C(=O)CC4=CC(=CC=C4)[N+](=O<br />)[O-]
InChI
1S/C22H25N3O3/c1-23(21(26)14-16-7-6-9-18(13-16)25(27)28)22-19-10-3-2-8-17(19)15-20(22)24-11-4-5-12-24/h2-3,6-10,13,20,22H,4-5,11-12,14-15H2,1H3/t20-,22?/m0/s1
InChIKey
ZSDAQBWGAOKTSI-AIBWNMTMSA-N
CAS Number
CAS 130610-93-4
PubChem Compound ID
65964
PubChem Substance ID
43122697, 51033484, 57315863, 104335144, 117381256, 134339974, 134340284, 135025719
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 545439Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003260)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.