Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08YHS
|
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| Former ID |
DIB015014
|
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| Drug Name |
Linopirdine
|
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| Synonyms |
AVIVA; Linopirine; DuP-996
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| Drug Type |
Small molecular drug
|
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| Company |
Bristol-Myers Squibb Pharma Co
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| Structure |
|
Download2D MOL |
|||
| Formula |
C26H21N3O
|
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| InChI |
InChI=1S/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2
|
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| InChIKey |
YEJCDKJIEMIWRQ-UHFFFAOYSA-N
|
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| CAS Number |
CAS 105431-72-9
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
854025, 4659686, 7979778, 8152470, 11111362, 11114259, 12014138, 14927733, 17405293, 24263040, 24277846, 29223046, 46500471, 47206562, 48259468, 50070441, 50071084, 50104972, 50104973, 53777838, 57322057, 57654323, 77625157, 85177305, 85231103, 85788683, 90341523, 92304330, 103314113, 104304940, 121361490, 124749952, 124800387, 124880516, 124880517, 126407736, 126679061, 129783712, 135028219, 135650523, 137156939, 144203728, 162206962, 162224821, 163049819, 163564686, 170466342, 174006298, 178125900, 179149530
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| Target and Pathway | |||||
| Target(s) | Potassium voltage-gated channel subfamily KQT member 3 | Target Info | Modulator | [531275] | |
| KEGG Pathway | Cholinergic synapse | ||||
| WikiPathways | Potassium Channels | ||||
| L1CAM interactions | |||||
| References | |||||
| Ref 531275 | The M-channel blocker linopirdine is an agonist of the capsaicin receptor TRPV1. J Pharmacol Sci. 2010;114(3):332-40. | ||||
| Ref 539676 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2599). | ||||
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