TTD | Drug: D05COG

Drug General Information
Drug ID	D05COG
Former ID	DIB013764
Drug Name	DU-1777
Drug Type	Small molecular drug
Indication	Hypertension [ICD9: 401; ICD10:I10-I16]		Terminated	[545072]
Company	Dainippon Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Formula	C26H37N5O7
Canonical SMILES	N1([C@@H](C[C@H]2[C@@H]1CCCC2)C(=O)O)C(=O)CC[C@@H](NC(=<br />O)[C@@H](NC(=O)c1cnccc1)CCCCN)C(=O)O
CAS Number	CAS 116662-73-8
PubChem Compound ID	3081108
Target and Pathway
Target(s)	Angiotensin-converting enzyme	Target Info	Inhibitor	[533641]
KEGG Pathway	Renin-angiotensin system
	Chagas disease (American trypanosomiasis)
	Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway	Angiotensin Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	ACE Inhibitor Pathway
WikiPathways	Metabolism of Angiotensinogen to Angiotensins
References
Ref 545072	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002041)
Ref 533641	Antihypertensive properties of a new long-acting angiotensin converting enzyme inhibitor in renin-dependent and independent hypertensive models. Arzneimittelforschung. 1995 Aug;45(8):853-8.

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Drug Information