Drug General Information
Drug ID
D0R3DN
Former ID
DIB006018
Drug Name
CPX
Synonyms
Cystic fibrosis therapy (CPX), SciClone
Drug Type
Small molecular drug
Indication Cystic fibrosis [ICD9: 277; ICD10:E84] Phase 2 [467606], [533629]
Company
National Institutes of Health
Formula
C11H16N4O2
InChI
InChI=1S/C11H16N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h7H,3-6H2,1-2H3,(H,12,13)
InChIKey
MJVIGUCNSRXAFO-UHFFFAOYSA-N
CAS Number
CAS 102146-07-6
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Adenosine receptor Target Info Modulator [533629]
References
Ref 467606(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 427).
Ref 533629CPX, a selective A1-adenosine-receptor antagonist, regulates intracellular pH in cystic fibrosis cells. Am J Physiol. 1995 Jul;269(1 Pt 1):C226-33.
Ref 533629CPX, a selective A1-adenosine-receptor antagonist, regulates intracellular pH in cystic fibrosis cells. Am J Physiol. 1995 Jul;269(1 Pt 1):C226-33.

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