Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X4ZL
|
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| Former ID |
DIB003476
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| Drug Name |
AN-1792
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| Synonyms |
Betabloc; AIP-001
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| Drug Type |
Small molecular drug
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 2 | [521492] | ||
| Company |
Elan Pharmaceutical Research
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| Structure |
|
Download2D MOL |
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| Formula |
C16H26ClNO
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| Canonical SMILES |
CCC(C)[NH2+]CC(C1=CC2=C(CCCC2)C=C1)O.[Cl-]
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| InChI |
1S/C16H25NO.ClH/c1-3-12(2)17-11-16(18)15-9-8-13-6-4-5-7-14(13)10-15;/h8-10,12,16-18H,3-7,11H2,1-2H3;1H
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| InChIKey |
KHBXORBAOCQNMC-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528396] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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