Drug Information
Drug General Information | |||||
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Drug ID |
D07PMG
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Former ID |
DIB004594
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Drug Name |
Afeletecan
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Synonyms |
Afeletecan hydrochloride; Camptothecin glycoconjugate, Bayer; Topoisomerase I inhibitors, Bayer
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Drug Type |
Small molecular drug
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Indication | Breast cancer [ICD9: 174, 175; ICD10:C50] | Phase 1 | [547154] | ||
Company |
Bayer AG
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Structure |
Download2D MOL |
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Formula |
C45H49N7O11S
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Canonical SMILES |
n12c(c3c(C2)cc2c(n3)cccc2)cc2c(c1=O)COC(=O)[C@]2(OC(=O)<br />[C@@H](NC(=O)[C@@H](NC(=S)Nc1ccc(O[C@@H]2[C@H]([C@@H]([<br />C@@H]([C@@H](O2)C)O)OC)O)cc1)Cc1nc[nH]c1)C(C)C)CC
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [544231] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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