Drug Information

Drug General Information
Drug ID
D02JIN
Former ID
DIB005192
Drug Name
264W94
Synonyms
GW-264
Drug Type
Small molecular drug
Indication Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] Phase 2 [531629], [541657]
Company
Glaxo Wellcome plc
Structure
Download
2D MOL

3D MOL
Formula
C23H31NO4S
InChI
InChI=1S/C23H31NO4S/c1-5-7-13-23(6-2)16-29(25,26)21-15-20(28-4)19(27-3)14-18(21)22(24-23)17-11-9-8-10-12-17/h8-12,14-15,22,24H,5-7,13,16H2,1-4H3/t22-,23-/m1/s1
InChIKey
CKFWDLFFXXVSBJ-DHIUTWEWSA-N
CAS Number
CAS 178961-24-5
PubChem Compound ID
9823277
PubChem Substance ID
14782330, 14880132, 24126343, 44859233, 76164282, 103352093, 104025005, 127637405, 142461805, 178103143, 224650550, 227605286
Target and Pathway
Target(s) Ileal bile acid transfer Target Info Modulator [531629]
KEGG Pathway Bile secretion
Reactome Recycling of bile acids and salts
WikiPathways Bile acid and bile salt metabolism
References
Ref 531629Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E68-76.
Ref 541657(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6529).
Ref 531629Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E68-76.

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